microbiome

Reversing the damage of Antibiotics on your Gut Microbiota

People with acne are intimately familiar with gut microbiota.  Having severe or moderate acne probably means you have cycled through tetracycline, minocycline, Azythromycin, and doxcycline, among others (these are the ones I have used)…

Unfortunately for us, research in the past decade is indicating that these bacteria are pretty damn important for our systemic health.  I have gone down the rabbit hole of gut testing–I have already used Ubiome (many times), American Gut (once), and the more comprehensive Genova Stool Test (results already posted).  I am not going to fool you into thinking that these are diagnostic or incredibly actionable at this point.  Most of it has been interesting, but it is still somewhat preliminary.  Have I been able to ‘target’ and change these things?  Not really.  I have been messing around with DIY fecal transplants, which I will do a blog post about soon (yes, fecal transplants are a thing but the FDA only allows it to be performed clinically for a very small number of conditions, unfortunately).

As a general rule of thumb, I always participate in research.  I recently participated in Ubiome’s mental health study.  I was very impressed and look forward to seeing the results.  I also received a free gut kit from it.

Another company that I have been really impressed with, and testing with of recently, is The Biocollective.  Martha Carlin, the CEO is awesome.  Her TED talk about the gut microbiota of Parkinson’s patients is here: http://tedxtalks.ted.com/video/Do-Gut-Microbes-Predict-or-Caus

Martha is  dead set on figuring out how the gut microbiome interacts with human health.  To get your gut sequenced, check out the website.  You can get the basic bird’s eye view of your gut bacteria done for free.  To get fungi, viruses, parasites, and bacteria checked, you can use the code word CAND50 for 50% off–this brings the standard kit’s price to $275– a good deal in this world.  And I am sure the price will drop in coming years as the price of sequencing continues to drop.  So if you take a shit–get tested.  It isn’t tough, the data benefits us all as we learn about us–the super-organisms that we are.

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Acne Revolution and Microbiome Insights

Ben at Acne Revolution has been doing some interesting work into the microbiome of people with acne and other conditions. He was recently featured on the UBIOME blog here.  I encourage you to check out his blog and perhaps perform your own experiments through Ubiome, which is revolutionizing Microbiome research. (also for redditors, /r/microbiome has a lot of good links on the subject)

Ubiome is very affordable at $89 per stool kit.  It is not as comprehensive and diagnostic as the Genova stool analysis, but it will do much more to move research in that area forward.

I am very interested in individual bacteria such as Akkermansia Mucinophilia (which I had very low levels of).  Akkermansia Mucinophilia has been show to play an important role in intestinal health and in preventing diabetes and obesity.  For those with mental health conditions, microbiome research will hopefully revolutionize psychiatry.

 Here is Ben’s post reviewing some of the insights that I have found.

The more people we can get doing this sort of thing, the better.

Also in other news, for Arizonan readers, self testing just became much easier and cheaper through Theranos.  This should spread throughout the country quickly, making self-testing much more affordable and easier.