inflammation

Reversing the damage of Antibiotics on your Gut Microbiota

People with acne are intimately familiar with gut microbiota.  Having severe or moderate acne probably means you have cycled through tetracycline, minocycline, Azythromycin, and doxcycline, among others (these are the ones I have used)…

Unfortunately for us, research in the past decade is indicating that these bacteria are pretty damn important for our systemic health.  I have gone down the rabbit hole of gut testing–I have already used Ubiome (many times), American Gut (once), and the more comprehensive Genova Stool Test (results already posted).  I am not going to fool you into thinking that these are diagnostic or incredibly actionable at this point.  Most of it has been interesting, but it is still somewhat preliminary.  Have I been able to ‘target’ and change these things?  Not really.  I have been messing around with DIY fecal transplants, which I will do a blog post about soon (yes, fecal transplants are a thing but the FDA only allows it to be performed clinically for a very small number of conditions, unfortunately).

As a general rule of thumb, I always participate in research.  I recently participated in Ubiome’s mental health study.  I was very impressed and look forward to seeing the results.  I also received a free gut kit from it.

Another company that I have been really impressed with, and testing with of recently, is The Biocollective.  Martha Carlin, the CEO is awesome.  Her TED talk about the gut microbiota of Parkinson’s patients is here: http://tedxtalks.ted.com/video/Do-Gut-Microbes-Predict-or-Caus

Martha is  dead set on figuring out how the gut microbiome interacts with human health.  To get your gut sequenced, check out the website.  You can get the basic bird’s eye view of your gut bacteria done for free.  To get fungi, viruses, parasites, and bacteria checked, you can use the code word CAND50 for 50% off–this brings the standard kit’s price to $275– a good deal in this world.  And I am sure the price will drop in coming years as the price of sequencing continues to drop.  So if you take a shit–get tested.  It isn’t tough, the data benefits us all as we learn about us–the super-organisms that we are.

Acne and Inflammatory Markers

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I just wanted to get this out there.  Acne does not seem to be related to inflammatory markers, at leas the ones presented here.  A suspicion I have is that acne is related to interleukin 1beta, although that is not measured on this test.

From my findings acne seems to be related much more to insulin resistance instead of markers for heart disease. 

On my next post I will document potential integrative pharmaceuticals for acne (life is short and while foods are the basis for health, not all problems can be overcome in a timely fashion with kale and coconut oil).  I will also upload another test, but the internet is so damn slow right now…

Also HDL Labs has a great basic panel and if anyone is looking for blood testing they should consider their basic panel.

Basic Blood Workup: Correlations We Can Draw

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april(1)0002

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Date: April 18,2013

Number of Lesions: 7

Medications/Diet/Supplements: Zyrtec 10 mg, Vit D, Animal Pak Multivitamin, NAC 1200 mg, Typical Diet with Beef Liver 1x per week

Correlations:  HDL cholesterol and fasting blood glucose correspond to acne. (Lower HDL = more acne) (Higher fasting blood sugar= more acne)

C-reactive Protein did not correlate with acne, as levels were great.  C-reactive Protein is an inflammatory marker.

Acne doesn’t necessarily correspond to testosterone levels necessarily, but it does seem to have some relation to estrogen (estradiol), for whatever reason.